THE

SARPONG

GROUP

 

exploring organic chemistry through

total synthesis and methods development

 

Our ResearchOur Values

Research Interests

Natural Products

Natural products provide a platform for developing solutions to longstanding problems in chemical synthesis. Our group does this through the development of novel strategies toward challenging targets.

Methods Development

Development of new methods provides powerful tools to implement strategies for synthesis. Among our interests are new ways to build and cleave carbon-carbon bonds through skeletal rearrangements.

Check out our virtual lab tour for visit weekend!

Group News

August 16, 2020

Congratulations to “Team Phomactins” on the publication in JACS of the full synthetic details of their work on these fascinating molecules. We are grateful to all our collaborators, especially the Berlinck group, for the work on other aspects of these molecules which was reported earlier in Nature Chemistry.

August 11, 2020

Congrats to Justin and thanks to our collaborators at Merck for including us on an enjoyable project, out in Organic Letters, exploring novel aspects of HLF chemistry! 

August 10, 2020

Check out this editorial on diversity and inclusion in chemistry written by Richmond, Sarah Reisman, Matt Sigman, and Tehshik Yoon out today in JOC, OLOrganometallics, and ACS Central Science!

August 2, 2020

Congratulations to Shelby McCowen, who has been awarded a University of California Cancer Research Coordinating Committee (CRCC) Fellowship for her work on the synthesis of highly bridged natural products that exhibit anti-cancer properties.

July 6, 2020

Congrats to Meggie on being awarded a Berkeley Chemistry Achievement Prize (CAP)! Meggie’s work as Faculty Support Administrator is invaluable to our group and we’re so lucky to work with her!

Twitter Feed

We're proud to announce a new policy that will allow our authors an easy way of changing the name used on previous publications. Read more about this new policy here: https://t.co/CALAWDRIvq

Our work on programed sequential additions to halogenated mucononitriles has been uploaded to ChemRxiv. Check it out. Congrats Adam Zahara, Dr. Elsa Hinds and Andrew Nguyen.

https://t.co/eUv0qOBrht

[email protected]_acsprof's #ACSFall2020 networking session ft @irv_does_chem on trans scholars' rights was stellar!✨Support the trans community & their efforts in better name change policies in publication spaces by signing the petition: https://t.co/6Ith2yqC1I #ChemTwitter #RealTimeChem

Check out Richmond's talk from yesterday's @AmerChemSociety symposium to celebrate the ACS PRF!
https://t.co/AYTLI5Em6o

Thanks to our collaborators at Merck for including us on an enjoyable project exploring novel aspects of HLF chemistry resulting in this @JOC_OL publication!
https://t.co/nCJOznsbFl

Congratulations to "Team Phomactins" on the full publication of their work on these molecules in @J_A_C_S. We are grateful to our collaborators, especially the Berlinck group, for the work on other aspects of these molecules which was reported earlier https://t.co/oLoI7uxrv1

🧪 Meet Prof Richmond Sarpong, #BlackInChem rockstar and natural product pro @UCBerkeley. Sarpong became interested in chemistry as a child in 🇬🇭. He develops new bioactive molecules for the treatment of neurodegenerative disease 💊. New @Wikipedia page: https://t.co/sUzvY5zrC9

4

#BlackInOrganic organic chemistry is my passion. Thankful for all the love and support that helped me navigate from Kinston NC to NCSU to Berkeley (@SarpongGroup) to Emory (Davies lab) to start my own lab @SmwhLab at UNC @uncchemistry. Thanks @jmhooker for giving me my first 1/2

For #BlackinOrganic we're highlighting the man himself... Richmond! His favorite purification technique: "I have always loved slow flash columns because you can still read papers between collecting fractions" He wants to thank the group from 2004-today!! https://t.co/PNi73QPdW7

2

For #BlackinOrganic, my favorite purification technique is recrystalization from my undergrad #BlackinInorganic days, which I never do in lab these days. More practically you’ll find me running a column. I work in the @SarpongGroup, a total synthesis & methods development lab 1/4

It's #BlackinOrganic day in #BlackinChem week! Here's a couple of fabulous @ScienceMagazine papers to have another look back at. First up is @SarpongGroup slicing through C-C bonds! https://t.co/9yrFP7JBe6

Another great #socialtuesday with the group, great to learn the origin story from ⁦@sarah_reisman⁩ and ⁦@SarpongGroup⁩ re their recent article also with ⁦@TehshikYoon⁩ and ⁦@Sigman_Lab⁩:

https://t.co/jDoC5dS3A9

Check out this editorial written by Richmond, @sarah_reisman, @Sigman_Lab , and @TehshikYoon titled "Organic Chemistry: A Call to Action for Diversity and Inclusion" in @JOC_OL, @Orgmet_ACS, and @ACSCentSci https://t.co/QwygLLOeBk

Congratulations to 5th year grad student Shelby McCowen, who has been awarded a University of California Cancer Research Coordinating Committee (CRCC) Fellowship for her work on the synthesis of highly bridged natural products that exhibit anti-cancer properties!!

Our recent group meeting literature talk presentations are now available at https://t.co/w8FUbJQz8h! Check them out!

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Selected Publications

Deconstructive fluorination of cyclic amines by carbon-carbon cleavage

Science 2018, 361, 171–174.

Roque, J. B.; Kuroda, Y.; Göttemann, L. T.; Sarpong, R.

Isolation, Synthesis, and Bioactivity Studies of Phomactin Terpenoids

Nature Chemistry 2018, 10, 938–945.

Kuroda, Y.; Nicacio, K. J.; da Silva, I. A.; Leger, P. R.; Chang, S.; Gubiani, J. R.; Deflon, V. M.; Nagashima, N.;Rode, A.; Blackford, K.; Ferreira, A. G.; Sette, L. D.; Williams, D. E.; Andersen, R. J.; Jancar, S.; Berlinck, R. G. S.; Sarpong, R. 

Network-Analysis-Guided Synthesis of Weisaconitine D and Liljestrandinine


Nature
 2015528, 493–498.

Marth, C.J.; Gallego, G.M.; Lee, J.C.; Lebold, T.P.; Kulyk, S.; Kou, K.G.M.; Qin, J.; Lilien, R.; Sarpong, R. 

Professor Richmond Sarpong

College of Chemistry Executive
Associate Dean
~
Professor of Chemistry
~
B.A. – Macalester College
Ph.D. – Princeton University
Postdoc – Caltech
~

Richmond’s research interests are in the area of chemical synthesis with a special focus on the strategies and methods to prepare bioactive natural products. These studies are rooted in a strong foundation in the physical organic phenomena and mechanisms that guide organic transformations, with an ultimate eye to learn about and exploit the biological activity of the compounds that his laboratory prepares to improve and sustain quality of life.

Richmond’s Bio

Curriculum Vitae (CV)

Contact Us

8th Floor Latimer Hall,
UC Berkeley Campus
Berkeley, CA 94720

+1 510-644-4158

rsarpong [at] berkeley [dot] edu

Administrative Assistant

meggie [at] berkeley [dot] edu

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